Multiple Autoimmune Syndrome (MAS), AutoInflammatory Disease and Inflammation

Multiple Autoimmune Syndrome (MAS)For a long time, people who suffered from the seemingly related disorders known as multiple autoimmune syndrome (MAS) and autoinflammatory disease were thought to be hypochondriacs or lazy when they complained to their doctors about their symptoms: skin rashes, chronic fatigue, joint pain, unexplained fevers, chest pain and abdominal pain just to name a few.

Now, doctors and researchers have organized patients and their symptoms into two primary and related groups:

Painful Psoriasis: MAS & AutoInflammatory DiseaseWhile the two categories have distinct differences, they also have commonalities, the primary one being inflammation. With both types of conditions, the body’s immune system is “confused” and attacks itself.

Multiple Autoimmune Syndrome (MAS) occurs when a person has three or more autoimmune diseases simultaneously and one of them is a skin disorder such as psoriasis, scleroderma or vitiligo.

Autoinflammatory disease is also an autoimmune disorder, and comes under a number of different guises:

  • Familial Mediterranean Fever (FMF)
  • Behcet’s disease
  • Neonatal Onset Multisystem Inflammatory Disease (NOMID)
  • Tumor Necrosis Factor (TNF) receptor-associated periodic syndrome (TRAPS)
  • Deficiency of the interleukin-1 (IL-1) receptor antagonist (DIRA)

These inflammatory diseases cause problems that range from skin rashes, soresabdominal pain and joint pain, unexplained fevers, inflamed blood vessels, adrenal insufficiency /fatigue, inflammation (chronic) is at the root of most human diseases and heart failure.

Chronic inflammation is commonly associated with each type of MAS. It is believed the inflammation encourages T-cellsv, intended to defend the immune system for a short-term assault, to stay “on” and attack the body instead. This causes tremendous damage in various areas of the body depending upon which system the T-cells falsely identify as a harmful invader. If the chronic inflammation is in the brain it can contribute to Alzheimer’s or Parkinson’s for example, in the circulation system, heart disease or stroke. If fat cells are chronically inflamed, it begins the process of type 2 diabetes. Inflammation in the gut leads to a host of painful skin disorders, joint diseases and bowel diseases including cancer. Genes become damaged and the immune system’s ability to correctly function is further compromised.

Add into this equation the many toxins present in our modern food chain and environment, plus high-risk behavior such as overeating, a diet high in carbohydrates and bad fats, lack of exercise, smoking, too much alcohol consumption and you have the unhealthy beginnings of MAS. However, there are actions you can take to reclaim your health.

The degree to which multiple autoimmune syndrome and autoinflammatory disease can be remediated, and chronic inflammatory response “turned off”, with lifestyle changes such as an anti-inflammatory diet, supplements and exercise has been area of intense study for several years.

Some of our ProBoost customers have shared two excellent resources written for laymen, that provide enlightening, actionable and scientific information about the tremendous impact of diet, toxins and life choices on our immune system’s function and our health. In fact, one of our customers Endocrinologist gives a copy of the first book to each of her diabetic patients:

  • Clean by Dr. Alejandro Junger, Cardiology & Functional Medicine
  • Grain Brain by Dr. David Perlmutter, Neurology

Multiple Autoimmune Syndrome and AutoInflammatory Disease is not “in your head” or a sentence that you can do nothing about as you will discover in the two books above. No supplement supports healthy immune function like ProBoost Thymic Protein A. Here is a testimonial from a customer whose daughter has MAS.

“My 21 year old daughter has fibro, chronic fatigue, AZOOR, necrobiosis lipoidica, granuloma annulare, and irritable bowel syndrome IBS. We swear that ProBoost has helped with almost all of them. And the best part about ProBoost is it’s natural – no harsh drugs, no side effects. It seems every drug she takes requires yet another to offset the effects of each other. Not so with ProBoost. We are sold!”

– Melissa L. – CustomerOrder Proboost

Here is a link about how Thymic Protein A works to boost the human immune system. To order ProBoost click here

Diabetes and Chronic Inflammation – A Modern Day Epidemic with a Solution

This article is the first part in a two part series on the epidemic of diabetes and chronic inflammation.Diabetes Epidemic

  • Part 1 – A Modern Day Epidemic with a Solution
  • Part 2 – Empower Yourself: Take Control – Solutions to Prevent, Reverse and Control Diabetes

The Diabetes Epidemic

Almost 29 million people in the United States alone have diabetes – over 9% of the population. Of that number, the ADA (American Diabetes Association) estimates that 7 million are not aware they have the disease. In 1958 the number of people diagnosed with diabetes was 1.5 million. By 2010 that number had increased to epidemic proportions to 18.8 million.

Diabetes epidemic health care costsMedical expenses for people with diabetes are twice that of non-diabetics and the estimated total health care cost in the US in 2012 was $245 billion and growing.

The growth of pre-diabetes is also growing rapidly. The ADA reports that in 2012 there were 86 million cases in people aged 20 and older. An astounding 51% of these cases are in people 65+

We propose it is time for people to take control of this epidemic. Unlike type 1, type 2 diabetes can be prevented in many cases. Factors like diet, exercise, stress and genetics play a role. You may not be able to control your genetics but you can control other factors. Especially the factors that link diabetes to chronic inflammation brought on by poor diet, weight gain, stress and a sedentary lifestyle. An anti-inflammatory diet and moderate exercise can prevent and can even treat type 2 diabetes and does wonders for stress levels.

First, let’s look at the disease process and then the solutions which are offered in part 2 of this article.

Diabetes and the Complication

Diabetes Insulin Resistance

Photo courtesy of WebMd

Type 2 diabetes results when the body does not produce enough insulin or the body cannot use the insulin produced in the pancreas. Insulin is a hormone that controls the amount of sugar in the blood. When blood sugar is too high it becomes toxic.

Recent research shows that when chronic inflammation is triggered by excess fat in the body, particularly around the abdomen, it plays a significant part in the progression of type 2 diabetes.

When blood sugar levels are constantly high, over time it affects the heart, eyes, skin, kidneys, nerves, as well as other parts of the body. Often, people experience one or more of the associated complications prior to being diagnosed with type 2 diabetes:

  • Heart Disease – Diabetics are at twice the risk for heart attack and stroke than non-diabetics
  • Kidney DiseaseDiabetes can damage the kidneys due to overwork from high blood sugar. Over time it can cause kidney failure
  • Eye Complications – Diabetics have an increased risk of blindness, glaucoma and other vision related problems
  • Nerve Damage (neuropathy) – Damage occures  to the nerves throughout the body
  • Skin Issues – Diabetes can cause infections, open sores, and chronic itching. Skin related issue are often a first sign of diabetes.
  • Foot Related Issues – nerve damage, infections and impeded blood flow to the feet can lead to serious problems like chronic pain, gangrene and amputation
  • Dental – Diabetics are far more prone to problems with their teeth and gums. Gingivitis and periodontitis increase the risk for heart disease.

How Inflammation Develops

How fat produces inflammation

Graphic courtesy of The Scientist

Insulin’s effect on our internal organs and cells are influenced by many factors. The buildup of fat around the stomach and on major organs in the abdomen cause the immune system to produce chemicals that trigger inflammation.

Scientists and physicians are connecting the role of this type of inflammation in the advancement of chronic diseases like diabetes, heart disease, arthritis and other autoimmune disorders, premature aging as well as other types of immune dysfunction.

Inflammatory Chemicals Produced by the Immune System

High levels of inflammation where discovered decades ago in people that had type 2 diabetes. Inflammatory chemicals, produced by the immune system, called cytokines are often significantly higher in type 2 diabetes compared to people that are not diabetics. Cytokines are especially important in the immune system and host an array of actions that regulate health and disease when in balance, including inflammation. When not in balance, they can result in chronic inflammation.  

The two highest risk factors, obesity and inactivity, have long been known to promote the development of type 2 diabetes. Generally speaking, a high carbohydrate diet, which in high in inflammation producing foods like Omega 6  fatty acids and grain glutens is associated with both weight gain and triggering inflammatory chemicals.

So, how does extra weight and a sedentary life-style promote chronic inflammation and fuel the progress of diabetes?

Researchers made the connection between type 2 diabetes and elevated cytokine levels inside fat tissue. They concluded that this excess fat causes chronic, low levels of inflammation, causing the immune system to dysfunction. This dysfunction alters the action of the hormone insulin and insulin resistance developed. When chronic high blood sugar is accompanied by high blood pressure, bad cholesterol ratios and excess abdomen fat, it is referred to as Metabolic Syndrome, an all too common combination  in diabetes which substantially increase a person’s risk of heart attack, stroke and brain disorders.

Type 2 diabetes is in part a result of a vicious cycle. The body becomes less and less sensitive to insulin, resulting in insulin resistance which then leads to more inflammation. The rise of chronic inflammation causes more insulin resistance. As blood sugar levels rise more and more, it eventually results in type 2 diabetes. The resulting stress of deterioration in health also contributes to increased inflammation. In the earliest stages, type 2 diabetes is reversible so it pays to address as early as possible.

Diabetes Epidemic SolutionsThere are many things you can do to take charge. No…there is not a magic bullet, but life-style changes and taking supplements like thymic protein can calm chronic inflammation are the next best thing.  If you have type 2 diabetes or have been diagnosed as pre-diabetic, take heart, you can take control.

Part 2 – Empower Yourself: Take Control –Solutions to Prevent, Reverse and Control Diabetes

Chronic Inflammation Accelerates Aging – What You Can Do

This is the third part in our series on effect of chronic inflammation and its effect on longevity (see links to part 1 and 2 at bottom)

Chronic Inflammation Accelerates AgingChronic inflammation accelerates aging. It has been scientifically linked to what is termed, early biological aging. This accelerated process can prevent us from being as healthy and youthful as possible, even robbing us of the rewards of a life time of hard work.

Unlike acute inflammation, which is a lifesaving response that can last for seconds or days, chronic inflammation is like a wildfire that burns for long periods of time, progressively destroying tissue and creating disease.

So how does chronic inflammation accelerate the aging process and what can we do to prevent or stop it from affecting our quality of life, aging and health?

Normal Aging vs. Early Biological Aging

Effect of Chronic Inflammation on Stem CellsIn mammals, aging has been linked to the gradual loss of pools of unique cells known as stem cells, which have the extraordinary potential to develop into many different cell types in the body and are essential to repair and growth.

Stem cells are the earliest cell types and are responsible for replacing damaged or aging cells with new, high functioning cells. Additionally, mature cells are able to replicate and achieve a critical balance of new, high functional cells independent of the overall age of the biological system.

All stem cells, regardless of what part of the body they originate, have three common properties:

  • They are able to divide and renew themselves over long periods of time
  • They are unspecialized which gives them remarkable longevity
  • They can give rise to specialized cell types like muscle, nerve, brain, organ and skin cells

However, research has shown that once cells reach the Hayflick limit—an internal biologic clock that limits or stops further cell regeneration– they are both unable to replicate or replace low-functioning, aging cells with higher functioning ones.

Aging cells lose their regenerative potential over time and become low, functioning cells unable to carry out essential metabolic processes including immune functions. Furthermore, this process has been linked to the erosion of chromosomal structures, known as telomeres which are critical to cell regeneration and protection from diseases like cancer. This decline in cell functioning is the principle cause of accelerated aging. Other factors shown to accelerate this process are smoking, low levels of important vitamins, poor sleep habits and a diet high in inflammatory foods.

Cells that have reached their “Hayflick limit” have common characteristics. These include constantly secreting compounds that support chronic inflammation like pro-inflammatory cytokines and metallothioneins and mitogens.

Chronic Inflammation Accelerates AgingUnfortunately, this inflammatory environment has a cluster effect on all nearby cells, regardless of their age, status or role in the body. It alters the surrounding connective tissues and leads to the hyper-production of reactive oxygen species (ROS), a process that results in the inability of the immune system to maintain or mount an effective immune response due to suppression of the T-cells.

Advanced aging and chronic disease states like diabetes, heart disease, brain and movement disorders, cancer and autoimmune conditions are affected and accelerated by these biological processes.

Chronic Inflammation – Reduce it for your health and longevity

So what can an individual do to reduce chronic inflammation or even prevent it to life a longer, healthier life?

Here are five suggestions that have shown to reduce chronic inflammation:

  1. DietGet good amounts of Omega 3 fatty acids which are essential for a healthy inflammatory response but that also minimizes chronic inflammation which is the foundation for disease and painful conditions like rheumatoid arthritis.  Eating foods rich in Omega 3’s like fish, beans, nuts and some vegetables and taking supplements rich in these natural nutrients like DHA are easy and healthy.Reduce Omega 6 fatty acids, when in balance, play an important role in tempering inflammation. However, Omega 6’s have become a disproportionate part of our diets, having a dangerous effect on the pathways to chronic inflammation.  Baked goods, pastas, grains, meat and dairy are loaded with Omega 6 fatty acids. The number one inflammatory food is wheat gluten regardless of sensitivity.  A high carbohydrate diet in general means high Omega 6 consumption.
  2. Take digestive enzymes with bromelian, which is a natural anti-inflammatory. They help break down the byproducts of inflammation and allow for more efficient cellular repair.
  3. Efficient inflammation depends on a healthy immune system. As we age our body matures fewer immune cells (T-cells) as our thymus gland shrinks. Chronic inflammation accelerates the aging and disease process as T-cells dysfunction or are limited in their response. T-cells are matured by Thymic protein which produced in smaller amount as we age and eventually stops. People suffering from any type of chronic inflammatory condition can supplement Thymic Protein A (TPA) to the Thymus gland. Supplementation of TPA has even been shown to restore white blood cell count in patients undergoing chemotherapy treatments for cancer.In addition almost 70% of our immune system cells are found in the gastrointestinal tract, often referred to as the “little immune system”. Essential to the health of the immune cells in the bowel lining are friendly bacteria called probiotics.It is essential for anyone suffering with inflammation to take a well-balanced, broad spectrum probiotic on a daily basis.
  4. Water – It might sound too simple but water is the primary vehicle for all chemical reactions in the body including inflammation. It is needed to flush out toxins and for proper hydration. It is amazing how many people are actually somewhat dehydrated either from lack of drinking enough water or from over consumption of dehydrating liquids like caffeinated beverages and alcohol.
  5. Sleep – Quality sleep for 8 hours a night on a consistent basis is anti-inflammatory. It gives the body time to regenerate, heal and preform critical metabolic processes including flushing out toxins. Conversely, poor quality, chronic sleep deprivation is pro-inflammatory and allows build up of oxidated stress. Plan a regular bed-time, a quite environment and try a few spritz  of calming lavender mist for a good night’s sleep.Reduce Chronic Inflammation

At ProBoost Direct we are committed to educating and informing our customers and readers about how a healthy immune system can increase quality of life and longevity.  Unchecked chronic inflammation accelerates aging but it’s never too early or too late to take charge of your health!

To find out more about ProBoost Thymic Protein A and how it can impact wellness and longevity, please visit our website. 

Part 1: Heart Disease and ProBoost – The Inflammation Connection

Part 2: Rheumatoid Arthritis – The Inflammation Connection: Breaking the Cycle

Rheumatoid Arthritis – The Inflammation Connection: Breaking the Cycle

ProBoost for Rhumatoid Arthritis

This is the second part in our series on disease states and effect of chronic inflammation.

If you or someone you love suffers from rheumatoid arthritis, this article could be a turning point point in how to positively affect the progression of arthritis by implementing two healthy, sustainable changes in your daily routine.

What is Rheumatoid Arthritis – The Inflammation Connection

Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disease that happens when the immune system attacks certain proteins in the body. Rheumatoid arthritis typically begins as joint pain in the fingers and toes. It also can cause disruption of cardiac, pulmonary, or cutaneous (skin) systems. Three people in every 10,000 persons will develop rheumatoid arthritis annually. RA most commonly manifests in patients between the ages of 35 and 50 years of age and affects women three times more often than men.

Rhumatoid arthritis in the fingersRheumatoid arthritis often results in joint disfigurement and chronic pain, creating chronic inflammation that leads to disruption of the body’s own tissues. RA affects synovial cells, an important source of fluid in joints, causing these cells to over grow in size and complexity (hypertrophy). This eventually leads to destruction of cartilage and bone.

The key immune cell players in RA include CD4 T cells, mononuclear phagocytes, fibroblasts, osteoclasts and neutrophils. These cells once activated, produce immune system proteins, which can lead to chronic inflammation. This inflammation and synovial cell hypertrophy is responsible for the destruction of bones, cartilage, tendons, ligaments, and even blood vessels.

RA is currently treated with anti-inflammatory drugs, disease-modifying antirheumatic drugs (DMARDs), immunosuppressants and steroids. Not a cure, but these drugs help slow the progress, control the inflammation as well as the pain associated with RA.

Unfortunately, mortality rates for patients with RA has shown to be 2.5 times greater than that of the than non-RA suffers of the same age. Infection, cancer, vasculitis and poor nutrition are implicated as significant causes of increased mortality in patients with rheumatoid arthritis.

Breaking the Cycle

Rhumatoid Arthritis - Break the Inflammation Cycle with ProBoostAside from taking extensive medications, some of which have sever side-effects, is there anything an individual can do to alleviate the symptoms and even the progression of RA?  The answer is yes.

Scientific researchers have known for sometime that the cornerstone of all degenerative conditions is chronic inflammation. We know that there are triggers within the immune system that cause this process but what triggers the triggers?

Diet – Let’s go back to the reference above about poor nutrition. There are numerous studies linking the progression and severity of RA symptoms to foods that promote chronic inflammation. According to Dr. David Perlmutter, a neurologist and author of “Grain Brain”, the most prominent dietary simulators of the inflammation pathways are gluten and a high carbohydrate diet in general. This is true regardless of being “gluten sensitive”. Not only does this deadly reaction to the food we put in our bodies affect the development and progression of RA, it causes inflammation in the brain, a precursor to Parkinson’s and Alzheimer’s disease. The connection to chronic inflammation and heart disease is well documented and RA suffers are at higher risk.

The Immune System – When the immune system is working optimally, the thymus gland makes proteins that mature and “educate” T-cells to stop and start the immune response. But the thymus gland shrinks with time and eventually stops producing the proteins required for the immune balance that replaces dysfunctional or declining T-cells by maturing and activating new ones.

In the past, there was no known way to replace the specific protein required to activate T-cells in the thymus, the cells at the very cornerstone of our ability to deal with disease, infection, prevent autoimmune response and inflammation.

In a discovery made by Dr. Terry Beardsley during research into the HIV virus, Thymic Protein A was discovered. Thymic Protein A (TPA) is the essential protein required by the thymus gland to mature and replace T-cells. Whether due to aging or genetics, when the thymus no longer has access to TPA, new T-Cells cannot be matured and utilized by the immune system thereby altering the body’s ability to mount a healthy immune response. The result is more vulnerability to infection and viruses, less ability to fight off diseases like cancer, increases in autoimmune issues like RA and potentially an uncontrolled inflammation response.

The good news for rheumatoid arthritis sufferers is there are Rheumatoid Arthritis Inflammation and ProBoost two ways to directly address the severity and progression of their condition.

First, as Dr. Perlmutter establishes via scientific research referenced in his book “Grain Brain” and through extensive use in his own practice, a gluten free diet and lowering carbohydrate intake has a remarkable impact on lowering inflammation markers which signals a reduction of chronic inflammation in the body. As one of our ProBoost customers reported, his endocrinologist  puts all her diabetic patients on a gluten free diet to reduce their risk of heart disease from chronic inflammation.

Second, supplemental replacement of Thymic Protein A boosts immunity by increasing the number of mature T-Cells needed by the immune system to properly regulate infection, inflammation and autoimmune response.

ProBoost, developed by Dr. Terry Beardsley, is a high concentration of pure Thymic Protein A derived from thymic extract. ProBoost is comes in single serving packets to be taken under the tongue (sub-lingual) for best results. It is recommended to take three packets a day in a chronic disease state which maybe tapered off to one or two a day depending on individual needs. Thymic Protein A has been found to be safe in any amount and has no known side effect even when used over long periods of time.

To read more on the immune system and rheumatoid arthritis, see our section on Disease States written by an immunology expert.

Order ProboostTo order ProBoost with fast, free shipping click here.

Heart Disease and ProBoost – The Inflammation Connection

Heart attack

First in the series about the chronic inflammation connection to disease,  premature aging and how Thymic Protein A helps boost immune response.

Heart disease, which is often preventable, is the leading cause of death for both men and women. According to the Center for Disease Control, one in every four deaths that occur in the United States every year occurs due to heart disease. Of the leading causes of heart disease, heart attack tops the list.

Approximately 715,000 Americans have heart attack every year. Heart attack and additional types of disease of the blood vessels of the heart (coronary artery disease) are responsible for over 100 billion dollars in healthcare costs annually.

Atherosclerosis is the cause of approximately 80% of all sudden deaths due to heart disease. Inflammation, now widely known to be a primary contributor to the disease process, is a significant contributor to atherosclerotic diseases.

Arterialsclaosis and inflammation by ProBoost DirectWith respect to heart disease, some heart attacks are caused by rupture of plaques that, in the process of rupture, injured the lining of the coronary artery. In response to this injury, inflammatory cytokines are released leading to the deposition of platelets and fibrin in the site of injury.

Acute inflammation is a normal and necessary response to pathogens, cell damage and irritations to remove the invader and being healing. Chronic inflammation leads to deposits of different cells and the destruction of tissue at the site of inflammation. This can process can lead to coronary thrombosis and cease the blood flow from that artery into the tissues of the heart. In the absence of blood flowing to the heart tissues, by rupture or blockage, a heart attack occurs.

Heart Attack One common symptom of heart attack is chest pain but according to WebMD, other symptoms are not as obvious, heart burn for example. Women tend to have slightly different symptoms and often confuse an upset stomach with flu or other problems.

Since our immune system’s T-cells play such an important factor in regulating the inflammatory response, it make sense to boost the effectiveness of our immune system by eliminating sources of chronic inflammation, which also increases pain levels, such as low immune function due to aging, certain foods like excessive carbohydrates and trans fats, stress and obesity.

If you are concerned about your inflammation levels, a simple blood test, the C-reactive protein (CRP) will show your markers for inflammation and in particular your risk for heart attack.

Heart Disease and Inflammation by ProBoost DirectAccording to WebMD, thymus extract can be used in many situations to bolster the immune system in dealing with infection, the effects of aging and for chronic inflammatory conditions.

Of course, any individual with chest pain should report to a doctor as soon as possible for treatment. Patients with cardiac risk factors, such as obesity, smoking, diabetes and hypertension are especially predisposed to having heart attack.

 For more information about ProBoost, derived from pure thymus extract, see our section on Thymic Protein A. ProBoost Thymic Protein A is Dr. approved.

Dr Trusted Certification for ProBoostDirect

 

Immune System Dysfunction and Thymic Protein A – Part 2: Look at the Source

High cost of health careIn part 1 of this blog, we talked about the enormous cost of Immune System Dysfunction. But  let’s look at a simple protein, one that our bodies make while we are young and diminishes as we age, that gives us the opportunity to optimize our immune system.

In the treatment of Immune Dysfunction, using thymic protein extracts has been researched since the 1970’s.  Considerable proof has been found that demonstrates that thymic proteins are useful for boosting immune function related to several diseases and disorders including, chronic infections (viral and bacterial), certain types of cancers and some auto-immune disorders.

Supplementation with Thymic Proteins can be used when the body’s own defense mechanisms are attacking self-tissue.  It was also discovered that repeated infections were reduced when sustained thymic proteins were use for a period of at least one year or more. The studies also confirmed that patients improved their immune parameters.

One of the most important indications for Thymic Protein A use in cancer patients, is the management of lymphopenia/leukopenia caused by chemotherapy and radiation treatments. Because of the severe drop in white blood cells, thymic protein use can bring up the white cell counts faster when they do fall or prevent dangerously low levels.  Patients taking thymic protein conclude their treatment with lesser side effects than patients who do not take it.

Clinical studies have shown that Thymic Protein A is indicated in the treatment of Rheumatoid Arthritis, Lupus, and Scleroderma.  These classic disorders occur because of an increase in antibody formation as a result of a high T-helper/T-suppressor ratio.  T-helper/T-suppressor ratios were returned to normal in three months when Thymic Protein A was used in patients with Rheumatoid Arthritis. Thymic protein use has shown significant improvements in the treatment of Chronic Fatigue, Cold and Flu, Fibromyaliga, Lupus Erythematosus, and Scleroderma.

There have been studies to determine if the use of thymic protein affects lymphocytes (T-cell), a type of white blood cell, plays in periodontal disease.  Neutrophils, another type of white blood cell, have an important role fighting infection and bacterial plaque infections in the mouth. This is especially important to people who have diabetes and the geriatric population because they are the most likely to have depressed levels of neutrophils. Neutrophil growth is encouraged by lymphocytes, which are in turn encouraged by thymic proteins.  Because of this relationship, lymphocytes have a major part in resisting periodontal disease, which can cause heart disease.

The bottom line is, our immune system ages over time just like the rest of our bodies. Add stress, medications, poor eating habits, environmental factors, and genetics to the mix, and it’s quite remarkable that we fend off as many illnesses as we do. However, at the source of healthy immune function we have to produce the correct cells to control inflammation and fight disease. To mature those cells, we need Thymic Protein A, which diminishes over time, as our thymic gland shrinks drastically with age.

Fortunately research has shown that supplementing thymic protein allows the immune system to mature the T-cells needed to its job. ProBoost Direct offers packets with 12 trillion molecules of  Thymic Protein A.

At ProBoost Direct, we are passionate about immune system support! To order ProBoost just give us a click.

Immune System Dysfunction and Thymic Protein A – Part 1

Immune System Dysfunction and Thymic Protein AOver 120 million Americans – one third of the population – are affected by a variety of health robbing dysfunctions of the immune system.  Several disorders and diseases that can result from immune dysfunction are:

It is impossible to accurately estimate the costs of immune dysfunction in terms of lost time at work, health care and prescription bills, not to mention the reduction in quality of life, but it’s not hard to image how huge the costs are given how many people are affected. Unfortunately, instead of looking for the origin of immune system dysfunction, enormous amounts of time and money are spent treating the resulting symptoms and illness – too often ineffectively.

One reason the immune system becomes dysfunctional is due to combined attacks.  When the immune system is suppressed or overworked, and the next infection, allergen or source of inflammation appears, it can be overwhelmed or unable to respond to the new threat.  Ideally, immune function is optimal in order to properly respond to infection, inflammation, or dangerous cells like cancer and tumors. If not, a new threat may emerge and the immune system may over or under-react. For example, chronic low-grade infections and autoimmune disorders occurring simultaneously are not uncommon when the immune system is dysfunctional.

Enter the Thymus Gland. Think of the thymus as the “brain” of the immune system. It is located below the breastbone and manufactures many diverse polypeptides that “program” some of the immune cells, which begin in the bone marrow.  These are called B-cell lymphocytes (white blood cells), which are encoded in the bone marrow and sent to the thymus for “instructions.” Other immune cells mature in the thymus gland by interacting with Thymic Protein A (TPA). Those are the T-lymphocytes (T-Cells), which patrol the body at all times, looking for threats. In order for the T-Cell to carry out its particular function, the receptor on the surface of the T-Cells links with the matching Thymic Protein A becoming immune-competent.

T-4 (CD4) helper cells and the T-8 (CD8) that differentiates into killer and suppressor cells are the two major types of T-Cells. The T-4 cells induce killer and suppressor cells and stimulate B-Cells to make antibodies and macrophages that eat pathogens like cancer cells. Killer cells kill.  They are immune-competent and can recognize tumor cells and cells that are virally infected. The killer cells attack the deviant cells.  Occasionally, killer cells will attack self-tissue, but the immune-competent suppressor cells will intercede to halt the assault if the immune system is optimal.

When the immune system is functioning correctly, the thymus makes proteins that “program” T-cells to start and stop immune response. However, the thymus shrinks over time and eventually ceases to produce the proteins essential to sustain immune balance by maturing new or replacing dysfunctional T-cells. Thymic gland atrophy is a function of aging, but can also be affected by a combination of elements, such as: genetic flaws, stress, disease, allergens, obesity, repeated exposure to toxic substances, medications, and a diet high in inflammation forming foods leading to chronic inflammation.

What if it were possible to regain more vitality, more health? Fortunately, now the immune system can be supplemented with the use of ProBoost Thymic Protein A

Next: Part 2 – Immune Dysfunction: Treatment at the Source